Factors responsible for descent of the testis

Factors responsible for descent of the testis are:

1. Shortening & traction of gubernaculum testis

2. Differential growth of body wall in relation to a
     relatively immobile gubernaculum

3. Raised intra-abdomenal pressure due to fecal accumulation and
    growth of intra abdominal  viscera.

4. Development and maturation of the epididymis.

5. Higher temperature in the abdomen

6. Hormaonal influence such as HCG,testosterone and DHT.

Factors responsible for maldescent of Testis:

Factors responsible for mal descent of Testis:

1.  Retroperitonial adhesion
2. Obstruction at the deep inguinal ring
3. Short Vas deferans
4. Short Pampiniform plexuses
5. Short Testicular vessels
6. Insufficient pull of gubernaculum testis
7. Abnormal attachment of the gubernaculum Testis
8. Gonadal dysgenesis
9. Deficient hormon stimulation
10. Deficency of gonadotropin & testosterone
11. Deficiency of Mullerian inhibitory factor from fetal      
       Sertilicells
12. Prune-Belly Syndrome .

Enzyme Inhabitors At a Glance

An enzyme inhabitor is a molecule that binds to the enzyme and decreases its activity. Since blocking an enzyme’s activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhabitors. They are also used in pesticides (Wikipedia)

Example:

1.       Alcohol consumed (beginners)  

2.       Antibiotics-

a.       Isoniazide

b.       Erythromycin

c.       Sulphonamide / Disulfirum

d.       Metronidazole

e.       Chloramphenicol

f.        Ketoconazole

g.       Ciprofloxacin

3.       Anti convalsant –Sodium valporate

4.       Cimetidine

5.       Allopurinol

6.       Chlorpromazine

7.       Imipramine

8.       Propranolol

9.       Metoprolol

10.   Interferone

11.   MAO inhabitors

Collected & Concise

Only for postgraduate students.