Sunday, 17 December 2017

Gluconeogenesis at a glance

 Substrate :http://medicalscienceeasy.blogspot.com/2017/12/substrstes-of-gluconeogenesis-at-glance.html

Site: liver 90% , Kidney 10%
Compartment: Mainly cytoplasm ,party in mitochondria
Nature : Anabolic
Rate limiting enzyme http://medicalscienceeasy.blogspot.com/2017/12/rate-limiting-enzymes-of-gluconeogenesis.html
 ATP needed: 6 ( to produce 1 glucose from substrate)
Source of ATP : Beta Oxydation of fatty acid
 Importance:

  • Maintain normal glucose concentration in fasting & starvation
  • Disposal of lactic acid & glycerol in normal state

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