Microbial Infections associated with Autoimmune diseases at a glance

Autoimmune diseases are often multi-organ diseases if unknown etiology. Although we do not know exactly what causes autoimmune diseases but there is increasing evidence that in many patients of chronic infections particularly bacteria and viruses play a important role in these diseases along with genetic predisposition and immune dysfunction.

Here some infectious microbial agents associated with Autoimmune diseases

Diseases	Infectious agents
1.Rheumatic Fever	Streptococcus pyogenes
2.Rheumatic Arthritis	Ebstein Barr virus Hepatitis C virus Escherichia Coli Mycobacteria sp.
3.Reiter’s Syndrome	Chalamydia trachomatis Shigella spe.
4.Guillain-Barre Syndrome	Campylobacter jejuni Cytomegalo virus Ebstein Barr virus
5.Multiple sclerosis	Ebstein Barr virus Hepatitis B virus Human herpes virus-6 Influenza A virus Measles virus
6.Myocarditis	Coxsacki virus B3 Cytomegalo virus Chalamydia trachomatis
7.Mysthenia Gravis	Hepatitis C virus
8.Primary Billiary cirrhosis	Escherichia Coli (Bacteria)
9.Greave Diseases	Yersinia enterocolitica (Bacteria)
10.Lupus	Ebstein Barr virus
11.Mixed Cryoglobulinaemia	Hepatitis C virus
12.Type 1 Diabetes Mellitus	Coxsacki virus B4 Cytomegalo virus Mumps Rubella
13.Allergetic Encephalitis	Measles virus
14.Scleroderma	Cytomegalo virus
15.HTLV associated Myopathy	Human T cell leukemia virus (HTLV)
16.Lyme Arthritis	Borrelia bugdorferi

Of course, not everyone who gets these infections will developed an autoimmune disease, since it seems that in addition to the infection, some sort of genetic predisposition is involved in the development of such conditions .

Collected and concise only for postgraduate students .