Sterilization is a process of absolute freeing of an article
from any microbial burden including spores.
Temperature of some effective and useful sterilization
methods are given below.
Name
|
Temperature
|
Time
|
Pressure
|
Hot air oven
|
190 .c
|
6 min(unwrapped
)
12 min (wrapped
)
|
Normal atmospheric pressure
|
180.c
|
30 min
|
||
170.c
|
1 hour
|
||
160.c
|
2 hour
|
||
Autoclave
|
121.c
|
15 min
|
15 psi (Ib/square
inch )
|
132.c
|
3 min
|
30 psi (Ib/square inch )
|
|
Tyndalization
|
100.c
|
30min (three successive days )
|
Normal atmospheric pressure
|
Inspissation
|
85.c
|
30min (three successive days )
|
Normal atmospheric pressure
|
Boiling
|
100.c
|
15 min
|
Normal atmospheric pressure
|
Pasteurization
(Holding )
|
63.c than rapidly cooling to 7.c
|
30 min
|
Normal atmospheric pressure
|
Pasteurization
(Flash)
|
72.c than rapidly cooling to 4.c
|
15 min
|
Normal atmospheric pressure
|
for more information please visit
1.http://www.pharmainfo.net/siriki-praveen-kumar/blog/principles-sterilization
Collected & Concise only for postgraduate student
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