Premalignant Conditions at a Glance

Pre -malignant conditions or pre-cancerous conditions are certain non neoplastic states or disorders which have a well defined association with cancer.

                        Examples        :

         1. Gastrointestinal tract:         

                        1. Oral cavity:             Leukoplakia

                         2. Esophagus:            a. Pulmmer -Vinsionsyndrome/

                                                                  Patersone-kelly syndrome

                                                                                               

                                                              b. Barret’s esophagus.

                         3. Stomach:                 Adenometous polyp

                                                              Chronic atropic gastritis

                                                              Chronic gastric ulcer

                         4. Small intestine:      Chron’s diseases

                         5. Large intestine:        Adenometous polyp

                                                               Chronic Ulcerative colitis

    6. Liver:                         Cirrhosis of liver

                        2. Skin -                      

§  Xeroderma pigmentosum

§  Dysplastic Nevi

§  Leukoplakia

§  Squamous cell carcinoma in situ / Bowen’s diseases

§  Radiodermatitis

§  Solar Acnitic Keratosis

                        3. Bones-                    

·         Paget’s diseases of bone

                        

                        4. Reproductive system

1.    Penis –                                Leukoplakia

2.    Female genital tract-          a.Endometrial Hyperplasia

                                             b. Cervical Dysplasia

                                             c.Dysplasia of vulva

                        5. Thyroid Gland:

                                               Autoimmune Thyroidities

                        6. Respiratory system:           

                                               Bronchial metaplasia

                                               Bronchial dysplasia




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