Tuesday, 24 May 2016

Type-I hypersensitive at a glance

Type-I hypersensitive or Anaphylaxis is an immediate hypersensitivity response triggered by IgE mediated mast cell degranulation,leafing to anapgylactic shock due to vasodilatation and smooth muscle contraction.

sign/symptoms :

  • Bronchospasm
  • Laryngeal oedema
  • Dyspnea
  • Hypotention
  • Abdominal pain
  • Diarrhoea
  • Vomiting
  • Generalized oedema


Example :
a.Systemic :

  • Bite of honey bees
  • Penicillin hypersensitive
  • Anti tetanus serum hypersensitive

b.Local :
  • Allergic rhinitis
  • Allergic conjunctivities
  • Skin allergy
  • Food allergy
  • Bronchial asthma
Collected & Concise only for postgraduate student

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